There is limited data on overdosage with irbesartan in humans; however, daily doses of 900 mg for 8 weeks are well-tolerated. Irbesartan overdose will most likely manifest as hypotension and tachycardia; bradycardia may also occur.
There is no specific information available on the treatment of irbesartan overdose. Closely monitor patient, institute symptomatic and supportive treatment. Suggested measures include induction of emesis and/or gastric lavage. Activated charcoal may be useful in the treatment of overdosage.
Irbesartan is not removed by hemodialysis.